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J ECT. 2012 Jun;28(2):84-6. doi: 10.1097/YCT.0b013e318238f01a.

Long-term follow-up of adolescents with resistant depression treated with repetitive transcranial magnetic stimulation.

Author information

  • 1Shalvata Mental Health Center, Hod HaSharon, Israel. gaddyma@clalit.org.il

Abstract

OBJECTIVE:

There is a paucity of information about repetitive transcranial magnetic stimulation (rTMS) as a treatment for adolescent depression, and there are no data about its long-term effectiveness and safety in this age group. The aim of this study was to evaluate symptoms of depression and cognitive functioning in young people who had been treated 3 years previously with rTMS for resistant depression.

METHODS:

Eight of 9 subjects who had participated in an open-label rTMS study were reassessed using the Child and Adolescent Depression Rating Scale-Revised and the Beck Depression Inventory II. Six of the subjects were also cognitively reassessed using the Cambridge Neuropsychological Test Automated Battery. The follow-up assessments were compared with the earlier pretreatment, inter-treatment and posttreatment assessments.

RESULTS:

At 3-year follow-up, there was no evidence of deterioration in symptoms of depression or cognitive functioning compared to the last assessment after rTMS.

CONCLUSION:

Preliminary evidence suggests that rTMS treatment of resistant depression in adolescents is not associated with long-term cognitive deterioration and that posttherapy clinical improvement can be maintained. It seems that some subjects may derive long-term benefit from the rTMS course.

PMID:
22531199
[PubMed - indexed for MEDLINE]
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