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Annu Rev Anal Chem (Palo Alto Calif). 2012;5:337-60. doi: 10.1146/annurev-anchem-062011-143152. Epub 2012 Apr 9.

Raman imaging.

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  • 1ChemImage Corporation, Pittsburgh, Pennsylvania 15208, USA.


The past decade has seen an enormous increase in the number and breadth of imaging techniques developed for analysis in many industries, including pharmaceuticals, food, and especially biomedicine. Rather than accept single-dimensional forms of information, users now demand multidimensional assessment of samples. High specificity and the need for little or no sample preparation make Raman imaging a highly attractive analytical technique and provide motivation for continuing advances in its supporting technology and utilization. This review discusses the current tools employed in Raman imaging, the recent advances, and the major applications in this ever-growing analytical field.

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