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Nat Immunol. 2012 Apr 18;13(5):423-7. doi: 10.1038/ni.2264.

Lessons learned from HIV-1 vaccine trials: new priorities and directions.

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  • 1Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.

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  • Nat Immunol. 2013 Apr;14(4):413.


A vaccine against human immunodeficiency virus (HIV) seems to be on the horizon. Correlates of risk of infection for [corrected] the RV144 vaccine trial have been found. There is understanding of what makes HIV envelope-specific antibodies broadly neutralizing and new T cell vaccine approaches can overcome virus variability.

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