Abstract
There has been considerable interest in the development of novel compounds with anticonvulsant, antidepressant, analgesic, anti-inflammatory, antiallergic, antipsychotic, antimicrobial, antimycobecterial, antitumour, antiviral and antitubercular activities. 1,3,4-oxadiazoles constitute an important class of compounds for new drug development. Therefore, many researchers have synthesized these compounds as target structures and evaluated their biological activities. These observations led to the development of new 1,3,4-oxadiazole derivatives. This review article describes the various biological activities associated with 1,3,4-oxadiazole ring system and is useful in guiding the researchers across the world working on this moiety and consequently have been instrumental in the advancement of 1,3,4-oxadiazole chemistry.
MeSH terms
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Animals
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Anti-Infective Agents / chemistry
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Anti-Infective Agents / pharmacology
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Anti-Inflammatory Agents / chemistry
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Anti-Inflammatory Agents / pharmacology
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Anticonvulsants / chemistry
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Anticonvulsants / pharmacology
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / pharmacology
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Drug Discovery*
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Enzyme Inhibitors / chemistry
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Enzyme Inhibitors / pharmacology
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Humans
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Hypoglycemic Agents / chemistry
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Hypoglycemic Agents / pharmacology
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Muscle Relaxants, Central / chemistry
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Muscle Relaxants, Central / pharmacology
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Oxadiazoles / chemistry*
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Oxadiazoles / pharmacology*
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Parasympatholytics / chemistry
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Parasympatholytics / pharmacology
Substances
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Anti-Infective Agents
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Anti-Inflammatory Agents
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Anticonvulsants
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Antineoplastic Agents
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Enzyme Inhibitors
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Hypoglycemic Agents
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Muscle Relaxants, Central
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Oxadiazoles
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Parasympatholytics