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Trends Microbiol. 2012 May;20(5):211-3. doi: 10.1016/j.tim.2012.03.003. Epub 2012 Apr 9.

Pertussis control: time for something new?

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  • 1Centers for Disease Control and Prevention, Division of Bacterial Diseases, 1600 Clifton Road, Mailstop C-25, Atlanta, GA 30333, USA.


Childhood acellular pertussis vaccines were licensed and implemented in the US in the 1990s following an effort to improve on the safety profile of whole-cell vaccines. However, waning of immunity from acellular vaccines may be driving the recent resurgence of pertussis, raising the need to consider new prevention strategies.

Published by Elsevier Ltd.

[PubMed - indexed for MEDLINE]
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