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Pediatr Blood Cancer. 2012 Nov;59(5):947-9. doi: 10.1002/pbc.24169. Epub 2012 Apr 10.

"Accelerated ear-age": a new measure of chemotherapy-induced ototoxicity.

Author information

  • 1Department of Otolaryngology and Communication Enhancement, Children's Hospital Boston, Boston, Massachusetts, USA. brian.fligor@childrens.harvard.edu

Abstract

Currently, there are several different scales that grade chemotherapy-induced ototoxicity. This report highlights how the implications of the conclusions drawn from each scale differ and compare these prior scales to a more functionally based scale developed at Children's Hospital Boston. Additionally, this report introduces the concept of "ear-age," akin to the age at which one would expect the observed decrease in hearing as a consequence of normative aging (but documented in a child or young adult following chemotherapy).

Copyright © 2012 Wiley Periodicals, Inc.

PMID:
22492682
[PubMed - indexed for MEDLINE]
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