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Curr Opin Plant Biol. 2012 Aug;15(4):483-92. doi: 10.1016/j.pbi.2012.03.008. Epub 2012 Apr 4.

Oomycetes, effectors, and all that jazz.

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  • 1The Sainsbury Laboratory, Norwich Research Park, Norwich NR4 7UH, United Kingdom.


Plant pathogenic oomycetes secrete a diverse repertoire of effector proteins that modulate host innate immunity and enable parasitic infection. Understanding how effectors evolve, translocate and traffic inside host cells, and perturb host processes are major themes in the study of oomycete-plant interactions. The last year has seen important progress in the study of oomycete effectors with, notably, the elucidation of the 3D structures of five RXLR effectors, and novel insights into how cytoplasmic effectors subvert host cells. In this review, we discuss these and other recent advances and highlight the most important open questions in oomycete effector biology.

Copyright © 2012 Elsevier Ltd. All rights reserved.

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