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Nephron Extra. 2011 Jan;1(1):69-72. doi: 10.1159/000331217. Epub 2011 Sep 8.

Crescentic glomerulonephritis in IgA multiple myeloma: a case report.

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  • 1Glomerulopathy Section, Universidade Federal de São Paulo, São Paulo, Brazil.

Abstract

BACKGROUND:

There are few reports of glomerulonephritis (GN) with crescents and a rapidly progressive course that lead to a diagnosis of a previously unsuspected B-cell dyscrasia.

CASE PRESENTATION:

We report a case of rapidly progressive GN: the patient showed no evidence of etiology at the time of biopsy and was diagnosed as IgA multiple myeloma (MM) during investigation based on a renal biopsy. He presented diffuse proliferative and exudative GN and marked plasma cell infiltration of the kidney.

CONCLUSION:

The present case raises the possibility that proliferative GN with crescents may be a rare mode of presentation of MM.

KEYWORDS:

B-cell dyscrasia; Crescents; Glomerulonephritis; Multiple myeloma; Rapidly progressive glomerulonephritis

PMID:
22470380
[PubMed]
PMCID:
PMC3290853
Free PMC Article
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