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J Rheumatol. 2012 May;39(5):946-8. doi: 10.3899/jrheum.111093. Epub 2012 Apr 1.

Tumor necrosis factor-α inhibitor use is not associated with lipid changes in rheumatoid arthritis.

Author information

  • 1Department of Rheumatology, Geisinger Health System, Danville, Pennsylvania 17822, USA. abili1@geisinger.edu

Abstract

OBJECTIVE:

To determine the association of use of tumor necrosis factor-α (TNF-α) inhibitors with differences in lipid levels in patients with rheumatoid arthritis (RA).

METHODS:

We studied 807 patients with incident RA to compare differences in lipid levels in TNF-α inhibitor users versus nonusers, with adjustment for relevant covariables.

RESULTS:

TNF-α inhibitor use was not associated with differences in levels of low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol (TC), triglycerides, LDL:HDL, or TC:HDL compared to nonusers.

CONCLUSION:

Use of TNF-α inhibitor was not associated with differences in lipid levels in patients with RA.

PMID:
22467937
[PubMed - indexed for MEDLINE]
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