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Prenat Diagn. 2012 Apr;32(4):336-43. doi: 10.1002/pd.2933.

Genomic microarrays: a technology overview.

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  • 1Laboratory for Cytogenetics and Genome Research, Centre for Human Genetics, University Hospital Leuven, K.U. Leuven, Leuven, Belgium.

Abstract

Genomic microarrays are now widely used diagnostically for the molecular karyotyping of patients with intellectual disability, congenital anomalies and autistic spectrum disorder and have more recently been applied for the detection of genomic imbalances in prenatal genetic diagnosis. We present an overview of the different arrays, protocols used and discuss methods of genomic array data analysis.

© 2012 John Wiley & Sons, Ltd.

PMID:
22467164
[PubMed - indexed for MEDLINE]
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