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Hematol Oncol Clin North Am. 2012 Apr;26(2):231-52, vii. doi: 10.1016/j.hoc.2012.02.006.

Why does my patient have thrombocytopenia?

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  • 1Yale University School of Medicine and Cancer Center, Veterans Affairs Connecticut Healthcare System, West Haven, CT 06516, USA.


Thrombocytopenia, usually defined as a platelet count of less than 150,000/μL, is a common reason for a hematology consult in both the inpatient and outpatient setting. In most patients, the cause of the thrombocytopenia can be identified and treated. This article reviews the clinical approach to the patient with thrombocytopenia, the mechanisms that underlie it, and the laboratory tests available to investigate it. A practical approach to the investigation and management of thrombocytopenia in the clinical settings commonly encountered by the hematology consultant is then described.

Published by Elsevier Inc.

[PubMed - indexed for MEDLINE]
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