Format

Send to:

Choose Destination
See comment in PubMed Commons below
Epidemiol Infect. 2012 Dec;140(12):2157-62. doi: 10.1017/S0950268812000520. Epub 2012 Mar 30.

Typing of the rabies virus in Chile, 2002-2008.

Author information

  • 1Sección Rabia, Subdepartamento Virología, Instituto de Salud Pública de Chile, Santiago, Chile. vyung@ispch.cl

Abstract

In Chile, dog rabies has been controlled and insectivorous bats have been identified as the main rabies reservoir. This study aimed to determine the rabies virus (RABV) variants circulating in the country between 2002 and 2008. A total of 612 RABV isolates were tested using a panel with eight monoclonal antibodies against the viral nucleoprotein (N-mAbs) for antigenic typing, and a product of 320-bp of the nucleoprotein gene was sequenced from 99 isolates. Typing of the isolates revealed six different antigenic variants but phylogenetic analysis identified four clusters associated with four different bat species. Tadarida brasiliensis bats were confirmed as the main reservoir. This methodology identified several independent rabies enzootics maintained by different species of insectivorous bats in Chile.

PMID:
22458941
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Cambridge University Press
    Loading ...
    Write to the Help Desk