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Eye Sci. 2012 Mar;27(1):44-6. doi: 10.3969/j.issn.1000-4432.2012.01.010.

Eyelid basal cell carcinoma arising on the site of a congenital port wine hemangioma.

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  • 1State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangzhou, China.



Only one previous case of eyelid basal cell carcinoma arising in a facial port wine stain without previous local radiotherapy has been reported. We now report a second case.


A 42-year-old female patient with eyelid basal cell carcinoma developing within a facial port wine stain underwent incisional biopsy, surgical excision and repair.


The patient had a mass at the inner canthus of the left eye for two years. She had a left facial congenital port wine hemangioma involving the left eyelid, for which no topical treatment had been given. Clinical examination disclosed a 1.5×1.2 cm ulcerated skin mass with irregular borders in the medial canthal region involving the medial aspect of both upper and lower left eyelids. Incisional biopsy revealed basal cell carcinoma. She underwent surgical excision by Mohs' technique and subsequent reconstructive eyelid surgery. The wound healed well postoperatively. At 2 years of follow up the patient showed no recurrence.


Patients with congenital facial port wine stain may develop basal cell carcinoma, and should be regularly monitored.

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