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Neuron. 2012 Mar 22;73(6):1060-2. doi: 10.1016/j.neuron.2012.03.006. Epub 2012 Mar 21.

Disintegrating brain networks: from syndromes to molecular nexopathies.

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  • 1Dementia Research Centre, Department of Neurodegenerative Disease, University College London Institute of Neurology, London WC1N 3BG, UK. jason.warren@ucl.ac.uk

Abstract

In this issue of Neuron, Raj et al. (2012) and Zhou et al. (2012) use graph theory to suggest that neurodegenerative diseases spread diffusively via intrinsic brain networks. These studies provide a powerful model for understanding and predicting disease-specific profiles of neurodegeneration.

Copyright © 2012 Elsevier Inc. All rights reserved.

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PMID:
22445334
[PubMed - indexed for MEDLINE]
PMCID:
PMC3389343
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