Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Trends Genet. 2012 Apr;28(4):175-84. doi: 10.1016/j.tig.2012.02.002. Epub 2012 Mar 14.

Dmrt genes in the development and evolution of sexual dimorphism.

Author information

  • Department of Evolution and Ecology, University of California-Davis, Davis, CA 95616 USA. akopp@ucdavis.edu

Abstract

Most animals are sexually dimorphic, but different taxa have different sex-specific traits. Despite major differences in the genetic control of sexual development among animal lineages, the doublesex/mab-3 related (Dmrt) family of transcription factors has been shown to be involved in sex-specific differentiation in all animals that have been studied. In recent years the functions of Dmrt genes have been characterized in many animal groups, opening the way to a broad comparative perspective. This review focuses on the similarities and differences in the functions of Dmrt genes across the animal kingdom. I highlight a number of common themes in the sexual development of different taxa, discuss how Dmrt genes have acquired new roles during animal evolution, and show how they have contributed to the origin of novel sex-specific traits.

Copyright © 2012 Elsevier Ltd. All rights reserved.

PMID:
22425532
[PubMed - indexed for MEDLINE]
PMCID:
PMC3350790
Free PMC Article

Images from this publication.See all images (5)Free text

Box 1 Figure I
Box 2 Figure I
Figure 1
Figure 2
Figure 3
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Write to the Help Desk