Activation state of platelets in experimental severe hemophilia A

Haematologica. 2012 Jul;97(7):1115-6. doi: 10.3324/haematol.2012.065235. Epub 2012 Mar 14.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blood Platelets / drug effects*
  • Blood Platelets / metabolism
  • Blood Platelets / pathology
  • Cells, Cultured
  • Crosses, Genetic
  • Disease Models, Animal
  • Fibrinogen / metabolism
  • Gene Expression / drug effects
  • Hemophilia A / genetics
  • Hemophilia A / metabolism*
  • Hemophilia A / pathology
  • Humans
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • P-Selectin / genetics
  • P-Selectin / metabolism
  • Peptide Fragments / pharmacology
  • Platelet Activation / drug effects*
  • Platelet Glycoprotein GPIIb-IIIa Complex / genetics
  • Platelet Glycoprotein GPIIb-IIIa Complex / metabolism
  • Protein Binding
  • Severity of Illness Index

Substances

  • P-Selectin
  • Peptide Fragments
  • Platelet Glycoprotein GPIIb-IIIa Complex
  • thrombin receptor peptide SFLLRNP
  • Fibrinogen