Cell Metab. 2012 Mar 7;15(3):273-4. doi: 10.1016/j.cmet.2012.02.008.

Autophagy works out.

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Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA. klionsky@umich.edu

Abstract

Autophagy is generally considered to be a cytoprotective response to stress, whether in the form of nutrient deprivation or the presence of dysfunctional organelles. He et al. now show in Nature that exercise-induced autophagy is needed for some of the beneficial effects of exercise on metabolism (He et al., 2012).

Comment on

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. [Nature. 2012]
Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis.He C, Bassik MC, Moresi V, Sun K, Wei Y, Zou Z, An Z, Loh J, Fisher J, Sun Q, et al. Nature. 2012 Jan 18; 481(7382):511-5. Epub 2012 Jan 18.

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PMCID:: PMC3308187

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