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J Invasive Cardiol. 2012 Mar;24(3):111-5.

In vivo comparison of Fourier-domain optical coherence tomography and intravascular ultrasonography.

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  • 1UT Southwestern and VA North Texas Healthcare System, Dallas, Texas, USA.

Abstract

BACKGROUND:

We sought to evaluate the findings of Fourier-domain optical coherence tomography (FD-OCT) and intravascular ultrasonography (IVUS) used for the in vivo assessment of coronary lesions.

METHODS:

We identified 19 lesions in 15 patients undergoing percutaneous coronary intervention that were assessed by both FD-OCT and IVUS and compared the lumen area and maximum/minimum lumen diameter at the site of maximum stenosis and the proximal and distal reference cross-sections.

RESULTS:

At the site of maximum stenosis, excellent correlation was found between FD-OCT and IVUS measurements: minimum lumen area (3.80 ± 2.36 mm² and 4.60 ± 2.13 mm², respectively; P=.002; Spearman's ρ = 0.94), maximum lumen diameter (2.30 ± 0.79 mm and 2.54 ± 0.60 mm, respectively; P=.005; Spearman's ρ = 0.93), and minimum lumen diameter (1.89 ± 0.69 mm and 2.24 ± 0.54 mm, respectively; P=.0001; Spearman's ρ = 0.90). Weaker correlations were found between FD-OCT and IVUS measurements of the proximal reference lumen area (4.74 ± 1.86 mm² and 5.16 ± 2.10 mm², respectively; P=.33; Spearman's ρ = 0.76) and distal reference lumen area (5.14 ± 1.60 mm² and 5.47 ± 2.45 mm², respectively; P=.144; Spearman's ρ = 0.72).

CONCLUSIONS:

Excellent correlation was found in FD-OCT and IVUS luminal measurements at the site of maximum coronary stenosis with weaker correlation at the proximal and distal reference cross-sections. FD-OCT minimum lumen area measurements were smaller than the IVUS measurements.

PMID:
22388302
[PubMed - indexed for MEDLINE]
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