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Appl Microbiol Biotechnol. 2012 Mar;93(6):2279-90. doi: 10.1007/s00253-012-3928-0. Epub 2012 Feb 18.

Industrial biotechnology of Pseudomonas putida and related species.

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  • 1HZI-Helmholtz Centre for Infection Research, Systems and Synthetic Biology, Braunschweig, Germany.


Since their discovery many decades ago, Pseudomonas putida and related subspecies have been intensively studied with regard to their potential application in industrial biotechnology. Today, these Gram-negative soil bacteria, traditionally known as well-performing xenobiotic degraders, are becoming efficient cell factories for various products of industrial relevance including a full range of unnatural chemicals. This development is strongly driven by systems biotechnology, integrating systems metabolic engineering approaches with novel concepts from bioprocess engineering, including novel reactor designs and renewable feedstocks.

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