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Praxis (Bern 1994). 2012 Feb 15;101(4):251-7. doi: 10.1024/1661-8157/a000837.

[Hormones as biomarkers for diagnosis and prognosis].

[Article in German]

Author information

  • 1Endokrinologie, Diabetologie und Metabolismus, Universit√§tsspital Basel.


Procalcitonin is a biomarker for estimating the likelihood of a bacterial infection. Procalcitonin-guided antibiotic therapy can reduce antibiotic overuse in respiratory tract infections. The differential diagnosis of water-electrolyte imbalances is challenging. Copeptin is co-secreted with arginine vasopressin (AVP) and is a reliable surrogate of plasma AVP. Copeptin may become a useful diagnostic tool in patients with polydipsia-polyuria syndrome and hyponatremia. Copeptin is also known to mirror different levels of stress. It appears to have an interesting potential as a new prognostic biomarker in patients with ischemic stroke. Biomarkers should not be used without the clinical context. They are meant to complement clinical judgment based upon a synthesis of available clinical and laboratory features in each patients.

[PubMed - indexed for MEDLINE]
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