Format

Send to:

Choose Destination
See comment in PubMed Commons below
Org Lett. 2012 Mar 2;14(5):1294-7. doi: 10.1021/ol300185u. Epub 2012 Feb 15.

Asymmetric synthesis of 4,8-dihydroxyisochroman-1-one polyketide metabolites using chiral hypervalent iodine(III).

Author information

  • 1Graduate School of Material Science, University of Hyogo, Kohto, Kamigori, Hyogo 678-1297, Japan. fuji@sci.u-hyogo.ac.jp

Abstract

Stereoselective oxylactonization of ortho-alkenylbenzoate with chiral hypervalent iodine is applied to the asymmetric synthesis of 4-oxyisochroman-1-one polyketide metabolites including 4-hydroxymellein (1), a derivative of fusarentin 2, monocerin (3), and an epimer of monocerin epi-3.

© 2012 American Chemical Society

PMID:
22335341
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Write to the Help Desk