Abstract
Several approaches for the inactivation of bacteriophage lambda, including UV germicidal irradiation (UVGI) and the chemical agents Virkon-S, Chloros, Decon-90, and sodium hydroxide (NaOH), were compared. Virkon, NaOH, and UVGI caused a ≥7-log(10) reduction in phage titers. This study successfully describes several methods with potential for bacteriophage inactivation in industrial settings.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antiviral Agents / metabolism*
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Bacteriophage lambda / drug effects
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Bacteriophage lambda / genetics
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Bacteriophage lambda / physiology*
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Bacteriophage lambda / radiation effects
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Microbial Viability / drug effects*
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Microbial Viability / radiation effects*
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Peroxides
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Sodium Compounds
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Sulfuric Acids
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Ultraviolet Rays*
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Viral Load
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Virus Inactivation*
Substances
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Antiviral Agents
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Peroxides
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Sodium Compounds
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Sulfuric Acids
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sodium hydride
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monoperoxysulfate