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Pediatr Infect Dis J. 2012 Mar;31(3):318-20. doi: 10.1097/INF.0b013e318243e502.

Cerebrospinal fluid enrichment broth cultures rarely contribute to the diagnosis of bacterial meningitis.

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  • 1Division of Infectious Diseases and the Division of Hospital Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. shah@cchmc.org

Abstract

This study included children undergoing lumbar puncture in the emergency department. Bacteria were isolated from 34 (1.7%) of 1898 cerebrospinal fluid (CSF) enrichment broth cultures; 30 were contaminants. The primary CSF Gram stain was negative in all specimens with a positive enrichment broth culture. Enrichment broth cultures rarely contributed to the diagnosis of bacterial meningitis, and positive CSF enrichment broth cultures contributed to diagnostic uncertainty.

[PubMed - indexed for MEDLINE]
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