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Head Neck. 2013 May;35(5):E164-6. doi: 10.1002/hed.22905. Epub 2012 Feb 6.

Lipoleiomyosarcoma of the larynx.

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  • 1Centre Hospitalier Régional et Universitaire de Tours, Service Oto-Rhino-Laryngologie et Chirurgie Cervico Faciale, Tours, France. jp.trijolet@univ-tours.fr

Abstract

BACKGROUND:

Lipoleiomyosarcoma is a rare tumor consisting of well-differentiated liposarcoma and leiomyosarcoma. The ear-nose-throat location of lipoleiomyosarcoma has not been previously described.

METHODS AND RESULTS:

A 37-year-old man with a dysphagia had a dyspnea after an endoscopy. A large tumor was exteriorized from the man's mouth. The lesion was pedicled to the epiglottis. A histologic examination determined that the tumor was a lipoleiomyosarcoma. MDM2 and CDK4 gene amplification were positive. Due to the risk of recurrence, a second intervention was performed to complete the excision.

CONCLUSION:

These tumors develop in cavities slowly and gradually. The treatment of this lesion is surgical with a sufficient resection margin.

Copyright © 2012 Wiley Periodicals, Inc.

PMID:
22307930
[PubMed - indexed for MEDLINE]
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