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Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases.

Park SJ, Ahmad F, Philp A, Baar K, Williams T, Luo H, Ke H, Rehmann H, Taussig R, Brown AL, Kim MK, Beaven MA, Burgin AB, Manganiello V, Chung JH.

Cell. 2012 Feb 3;148(3):421-33. doi: 10.1016/j.cell.2012.01.017.


Recent advances in the study on resveratrol.

Nakata R, Takahashi S, Inoue H.

Biol Pharm Bull. 2012;35(3):273-9. Review.


Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans.

Timmers S, Konings E, Bilet L, Houtkooper RH, van de Weijer T, Goossens GH, Hoeks J, van der Krieken S, Ryu D, Kersten S, Moonen-Kornips E, Hesselink MK, Kunz I, Schrauwen-Hinderling VB, Blaak EE, Auwerx J, Schrauwen P.

Cell Metab. 2011 Nov 2;14(5):612-22. doi: 10.1016/j.cmet.2011.10.002.


SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function.

Price NL, Gomes AP, Ling AJ, Duarte FV, Martin-Montalvo A, North BJ, Agarwal B, Ye L, Ramadori G, Teodoro JS, Hubbard BP, Varela AT, Davis JG, Varamini B, Hafner A, Moaddel R, Rolo AP, Coppari R, Palmeira CM, de Cabo R, Baur JA, Sinclair DA.

Cell Metab. 2012 May 2;15(5):675-90. doi: 10.1016/j.cmet.2012.04.003.


Resveratrol improves health and survival of mice on a high-calorie diet.

Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA.

Nature. 2006 Nov 16;444(7117):337-42. Epub 2006 Nov 1.


Effect of resveratrol on fat mobilization.

Baile CA, Yang JY, Rayalam S, Hartzell DL, Lai CY, Andersen C, Della-Fera MA.

Ann N Y Acad Sci. 2011 Jan;1215:40-7. doi: 10.1111/j.1749-6632.2010.05845.x. Review.


Resveratrol and health--a comprehensive review of human clinical trials.

Smoliga JM, Baur JA, Hausenblas HA.

Mol Nutr Food Res. 2011 Aug;55(8):1129-41. doi: 10.1002/mnfr.201100143. Epub 2011 Jun 20. Review.


Finding a target for resveratrol.

Tennen RI, Michishita-Kioi E, Chua KF.

Cell. 2012 Feb 3;148(3):387-9. doi: 10.1016/j.cell.2012.01.032.


Resveratrol and diabetic cardiac function: focus on recent in vitro and in vivo studies.

Turan B, Tuncay E, Vassort G.

J Bioenerg Biomembr. 2012 Apr;44(2):281-96. doi: 10.1007/s10863-012-9429-0. Review.


Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.

Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J.

Cell. 2006 Dec 15;127(6):1109-22. Epub 2006 Nov 16.


Skin toxicity from external beam radiation therapy in breast cancer patients: protective effects of Resveratrol, Lycopene, Vitamin C and anthocianin (Ixor®).

Di Franco R, Calvanese M, Murino P, Manzo R, Guida C, Di Gennaro D, Anania C, Ravo V.

Radiat Oncol. 2012 Jan 30;7:12. doi: 10.1186/1748-717X-7-12.


What is new for an old molecule? Systematic review and recommendations on the use of resveratrol.

Vang O, Ahmad N, Baile CA, Baur JA, Brown K, Csiszar A, Das DK, Delmas D, Gottfried C, Lin HY, Ma QY, Mukhopadhyay P, Nalini N, Pezzuto JM, Richard T, Shukla Y, Surh YJ, Szekeres T, Szkudelski T, Walle T, Wu JM.

PLoS One. 2011;6(6):e19881. doi: 10.1371/journal.pone.0019881. Epub 2011 Jun 16. Review.


Resveratrol in medicinal chemistry: a critical review of its pharmacokinetics, drug-delivery, and membrane interactions.

Neves AR, Lucio M, Lima JL, Reis S.

Curr Med Chem. 2012;19(11):1663-81. Review.


Resveratrol attenuates obesity-associated peripheral and central inflammation and improves memory deficit in mice fed a high-fat diet.

Jeon BT, Jeong EA, Shin HJ, Lee Y, Lee DH, Kim HJ, Kang SS, Cho GJ, Choi WS, Roh GS.

Diabetes. 2012 Jun;61(6):1444-54. doi: 10.2337/db11-1498. Epub 2012 Feb 23.


Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation.

Lee H, Zhang P, Herrmann A, Yang C, Xin H, Wang Z, Hoon DS, Forman SJ, Jove R, Riggs AD, Yu H.

Proc Natl Acad Sci U S A. 2012 May 15;109(20):7765-9. doi: 10.1073/pnas.1205132109. Epub 2012 Apr 30.


Resveratrol inhibits inflammatory responses via the mammalian target of rapamycin signaling pathway in cultured LPS-stimulated microglial cells.

Zhong LM, Zong Y, Sun L, Guo JZ, Zhang W, He Y, Song R, Wang WM, Xiao CJ, Lu D.

PLoS One. 2012;7(2):e32195. doi: 10.1371/journal.pone.0032195. Epub 2012 Feb 21.


[Resveratrol: a neuroprotective polyphenol in the Mediterranean diet].

López-Miranda V, Soto-Montenegro ML, Vera G, Herradón E, Desco M, Abalo R.

Rev Neurol. 2012 Mar 16;54(6):349-56. Review. Spanish.


Resveratrol, a neuroprotective supplement for Alzheimer's disease.

Li F, Gong Q, Dong H, Shi J.

Curr Pharm Des. 2012;18(1):27-33. Review.


Resveratrol: potential as anticancer agent.

Aluyen JK, Ton QN, Tran T, Yang AE, Gottlieb HB, Bellanger RA.

J Diet Suppl. 2012 Mar;9(1):45-56. doi: 10.3109/19390211.2011.650842. Review.


Cancer chemopreventive activity of resveratrol, a natural product derived from grapes.

Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, Fong HH, Farnsworth NR, Kinghorn AD, Mehta RG, Moon RC, Pezzuto JM.

Science. 1997 Jan 10;275(5297):218-20.

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