Format

Send to:

Choose Destination
See comment in PubMed Commons below
PLoS Biol. 2012 Jan;10(1):e1001251. doi: 10.1371/journal.pbio.1001251. Epub 2012 Jan 31.

Reconstructing speech from human auditory cortex.

Author information

  • 1Helen Wills Neuroscience Institute, University of California Berkeley, Berkeley, California, United States of America. bpasley@berkeley.edu

Abstract

How the human auditory system extracts perceptually relevant acoustic features of speech is unknown. To address this question, we used intracranial recordings from nonprimary auditory cortex in the human superior temporal gyrus to determine what acoustic information in speech sounds can be reconstructed from population neural activity. We found that slow and intermediate temporal fluctuations, such as those corresponding to syllable rate, were accurately reconstructed using a linear model based on the auditory spectrogram. However, reconstruction of fast temporal fluctuations, such as syllable onsets and offsets, required a nonlinear sound representation based on temporal modulation energy. Reconstruction accuracy was highest within the range of spectro-temporal fluctuations that have been found to be critical for speech intelligibility. The decoded speech representations allowed readout and identification of individual words directly from brain activity during single trial sound presentations. These findings reveal neural encoding mechanisms of speech acoustic parameters in higher order human auditory cortex.

PMID:
22303281
[PubMed - indexed for MEDLINE]
PMCID:
PMC3269422
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Public Library of Science Icon for PubMed Central
    Loading ...
    Write to the Help Desk