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J Clin Microbiol. 2012 Apr;50(4):1422-4. doi: 10.1128/JCM.06702-11. Epub 2012 Feb 1.

Evaluation of new biomarker genes for differentiating Haemophilus influenzae from Haemophilus haemolyticus.

Author information

  • 1Meningitis and Vaccine Preventable Diseases Branch, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA. ale7@cdc.gov

Abstract

PCR detecting the protein D (hpd) and fuculose kinase (fucK) genes showed high sensitivity and specificity for identifying Haemophilus influenzae and differentiating it from H. haemolyticus. Phylogenetic analysis using the 16S rRNA gene demonstrated two distinct groups for H. influenzae and H. haemolyticus.

PMID:
22301020
[PubMed - indexed for MEDLINE]
PMCID:
PMC3318567
Free PMC Article
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