Send to:

Choose Destination
See comment in PubMed Commons below
J Clin Invest. 2012 Feb;122(2):436-9. doi: 10.1172/JCI62237. Epub 2012 Feb 1.

Synergy of understanding dermatologic disease and epidermal biology.

Author information

  • 1Department of Dermatology, University of Pennsylvania, 415 Curie Blvd, Philadelphia, Pennsylvania 19104, USA.

Erratum in

  • J Clin Invest. 2012 Mar 1;122(3):1131.


Dermatologic disease, although seldom life threatening, can be extremely disfiguring and interfere with the quality of life. In addition, as opposed to other organs, just the aging of skin and its adnexal structure the hair follicle can result in cosmetic concerns that affect most of us. The articles in this dermatology Review Series demonstrate recent progress in understanding the cell biology and molecular pathophysiology of the epidermis and hair follicles, which harbor keratinocyte and melanocyte stem cells. They reveal a dynamic relationship between research and clinical care: knowledge of dermatologic disease has facilitated the understanding of the biology of the epidermis and, in turn, progress in basic science has informed our understanding of disease. This type of synergy is a profound strength of clinical research of the type that the JCI is dedicated to publishing.

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Journal of Clinical Investigation Icon for PubMed Central
    Loading ...
    Write to the Help Desk