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    Results: 1 to 20 of 73

    1.

    Antigen 85C inhibition restricts Mycobacterium tuberculosis growth through disruption of cord factor biosynthesis.

    Warrier T, Tropis M, Werngren J, Diehl A, Gengenbacher M, Schlegel B, Schade M, Oschkinat H, Daffe M, Hoffner S, Eddine AN, Kaufmann SH.

    Antimicrob Agents Chemother. 2012 Apr;56(4):1735-43. Epub 2012 Jan 30.

    PMID:
    22290959
    [PubMed - in process]
    Free PMC Article
    2.

    Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis.

    Pantel A, Petrella S, Veziris N, Brossier F, Bastian S, Jarlier V, Mayer C, Aubry A.

    Antimicrob Agents Chemother. 2012 Apr;56(4):1990-6. Epub 2012 Jan 30.

    PMID:
    22290942
    [PubMed - in process]
    3.

    SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis.

    Tahlan K, Wilson R, Kastrinsky DB, Arora K, Nair V, Fischer E, Barnes SW, Walker JR, Alland D, Barry CE 3rd, Boshoff HI.

    Antimicrob Agents Chemother. 2012 Apr;56(4):1797-809. Epub 2012 Jan 17.

    PMID:
    22252828
    [PubMed - in process]
    4.

    A semimechanistic pharmacokinetic-enzyme turnover model for rifampin autoinduction in adult tuberculosis patients.

    Smythe W, Khandelwal A, Merle C, Rustomjee R, Gninafon M, Bocar Lo M, Sow OB, Olliaro PL, Lienhardt C, Horton J, Smith P, McIlleron H, Simonsson US.

    Antimicrob Agents Chemother. 2012 Apr;56(4):2091-8. Epub 2012 Jan 17.

    PMID:
    22252827
    [PubMed - in process]
    5.

    Reevaluation of the critical concentration for drug susceptibility testing of Mycobacterium tuberculosis against pyrazinamide using wild-type MIC distributions and pncA gene sequencing.

    Werngren J, Sturegård E, Juréen P, Ängebyc K, Hoffner S, Schön T.

    Antimicrob Agents Chemother. 2012 Mar;56(3):1253-7. Epub 2011 Dec 27.

    PMID:
    22203587
    [PubMed - in process]
    6.

    Resuscitation-promoting factors are required for β-lactam tolerance and the permeability barrier in Mycobacterium tuberculosis.

    Wivagg CN, Hung DT.

    Antimicrob Agents Chemother. 2012 Mar;56(3):1591-4. Epub 2011 Dec 12.

    PMID:
    22155826
    [PubMed - in process]
    7.

    Pharmacokinetics and pharmacodynamics of TMC207 and its N-desmethyl metabolite in a murine model of tuberculosis.

    Rouan MC, Lounis N, Gevers T, Dillen L, Gilissen R, Raoof A, Andries K.

    Antimicrob Agents Chemother. 2012 Mar;56(3):1444-51. Epub 2011 Dec 12.

    PMID:
    22155815
    [PubMed - in process]
    8.

    Aerosolized gentamicin reduces the burden of tuberculosis in a murine model.

    Roy CJ, Sivasubramani SK, Dutta NK, Mehra S, Golden NA, Killeen S, Talton JD, Hammoud BE, Didier PJ, Kaushal D.

    Antimicrob Agents Chemother. 2012 Feb;56(2):883-6. Epub 2011 Dec 5. Erratum in: Antimicrob Agents Chemother. 2012 Mar;56(3):1672.

    PMID:
    22143521
    [PubMed - indexed for MEDLINE]
    9.

    Importance of confirming data on the in vivo efficacy of novel antibacterial drug regimens against various strains of Mycobacterium tuberculosis.

    De Groote MA, Gruppo V, Woolhiser LK, Orme IM, Gilliland JC, Lenaerts AJ.

    Antimicrob Agents Chemother. 2012 Feb;56(2):731-8. Epub 2011 Dec 5.

    PMID:
    22143517
    [PubMed - indexed for MEDLINE]
    10.

    Phenylethyl butyrate enhances the potency of second-line drugs against clinical isolates of Mycobacterium tuberculosis.

    Grau T, Selchow P, Tigges M, Burri R, Gitzinger M, Böttger EC, Fussenegger M, Sander P.

    Antimicrob Agents Chemother. 2012 Feb;56(2):1142-5. Epub 2011 Nov 21.

    PMID:
    22106218
    [PubMed - indexed for MEDLINE]
    11.

    Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions.

    Kjellsson MC, Via LE, Goh A, Weiner D, Low KM, Kern S, Pillai G, Barry CE 3rd, Dartois V.

    Antimicrob Agents Chemother. 2012 Jan;56(1):446-57. Epub 2011 Oct 10.

    PMID:
    21986820
    [PubMed - in process]
    Free PMC Article
    12.

    Plasma drug activity assay for treatment optimization in tuberculosis patients.

    Heysell SK, Mtabho C, Mpagama S, Mwaigwisya S, Pholwat S, Ndusilo N, Gratz J, Aarnoutse RE, Kibiki GS, Houpt ER.

    Antimicrob Agents Chemother. 2011 Dec;55(12):5819-25. Epub 2011 Oct 3.

    PMID:
    21968363
    [PubMed - indexed for MEDLINE]
    Free Article
    13.

    Pharmacokinetics of isoniazid, rifampin, and pyrazinamide in children younger than two years of age with tuberculosis: evidence for implementation of revised World Health Organization recommendations.

    Thee S, Seddon JA, Donald PR, Seifart HI, Werely CJ, Hesseling AC, Rosenkranz B, Roll S, Magdorf K, Schaaf HS.

    Antimicrob Agents Chemother. 2011 Dec;55(12):5560-7. Epub 2011 Oct 3.

    PMID:
    21968358
    [PubMed - indexed for MEDLINE]
    Free Article
    14.

    Sterilizing activity of novel TMC207- and PA-824-containing regimens in a murine model of tuberculosis.

    Tasneen R, Li SY, Peloquin CA, Taylor D, Williams KN, Andries K, Mdluli KE, Nuermberger EL.

    Antimicrob Agents Chemother. 2011 Dec;55(12):5485-92. Epub 2011 Sep 19.

    PMID:
    21930883
    [PubMed - indexed for MEDLINE]
    Free Article
    15.

    Impact of Fgd1 and ddn diversity in Mycobacterium tuberculosis complex on in vitro susceptibility to PA-824.

    Feuerriegel S, Köser CU, Baù D, Rüsch-Gerdes S, Summers DK, Archer JA, Marti-Renom MA, Niemann S.

    Antimicrob Agents Chemother. 2011 Dec;55(12):5718-22. Epub 2011 Sep 19.

    PMID:
    21930879
    [PubMed - indexed for MEDLINE]
    Free Article
    16.

    Characterization of mutations conferring extensive drug resistance to Mycobacterium tuberculosis isolates in Pakistan.

    Ali A, Hasan R, Jabeen K, Jabeen N, Qadeer E, Hasan Z.

    Antimicrob Agents Chemother. 2011 Dec;55(12):5654-9. Epub 2011 Sep 12.

    PMID:
    21911575
    [PubMed - indexed for MEDLINE]
    Free Article
    17.

    Pharmacokinetic mismatch does not lead to emergence of isoniazid- or rifampin-resistant Mycobacterium tuberculosis but to better antimicrobial effect: a new paradigm for antituberculosis drug scheduling.

    Srivastava S, Sherman C, Meek C, Leff R, Gumbo T.

    Antimicrob Agents Chemother. 2011 Nov;55(11):5085-9. Epub 2011 Sep 6.

    PMID:
    21896907
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    Wild-type MIC distributions must be considered to set clinically meaningful susceptibility testing breakpoints for all bacterial pathogens, including Mycobacterium tuberculosis.

    Angeby K, Giske CG, Juréen P, Schön T, Pasipanodya JG, Gumbo T.

    Antimicrob Agents Chemother. 2011 Sep;55(9):4492-3; author reply 4493. No abstract available.

    PMID:
    21849570
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Clofazimine analogs with efficacy against experimental tuberculosis and reduced potential for accumulation.

    Lu Y, Zheng M, Wang B, Fu L, Zhao W, Li P, Xu J, Zhu H, Jin H, Yin D, Huang H, Upton AM, Ma Z.

    Antimicrob Agents Chemother. 2011 Nov;55(11):5185-93. Epub 2011 Aug 15.

    PMID:
    21844321
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    Optimizing second-line therapy for drug-resistant tuberculosis: the additive value of sequencing for multiple resistance loci.

    Heysell SK, Houpt ER.

    Antimicrob Agents Chemother. 2011 Aug;55(8):3968-9. No abstract available.

    PMID:
    21757612
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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