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J Med Case Rep. 2012 Jan 30;6:40. doi: 10.1186/1752-1947-6-40.

Pseudotumoral tracheobronchial amyloidosis mimicking asthma: a case report.

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  • 1Department of Lung Disease, Hassan II University Hospital of Fez, Fez, Morocco. moonserraj@yahoo.fr.

Abstract

INTRODUCTION:

Tracheobronchial amyloidosis is an uncommon localized form of amyloidosis that can simulate a tracheal tumor. Clinical signs are not specific and the diagnosis is rarely given before performing a bronchoscopy with multiples biopsies.

CASE PRESENTATION:

We report the case of a 60-year-old Moroccan woman, complaining of dyspnea and wheezing for three years, who was treated at our institution for management of severe asthma. A bronchoscopy revealed a tumor formation of her trachea; multiples biopsies were performed and a diagnosis made of amyloid light-chain amyloidosis. She successfully received an endoscopic resection.

CONCLUSION:

This case highlights the importance of routinely carrying out an endoscopy in any patient complaining of atypical bronchial symptoms or with uncontrolled asthma. Tracheal amyloidosis is a rare disease, confirmed by histological examination of bronchial biopsies, and the treatment of choice is based on the bronchoscopic resection.

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