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Curr Biol. 2012 Jan 24;22(2):R52-4. doi: 10.1016/j.cub.2011.12.007.

Motor proteins: kinesin can replace Myosin.

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  • 1Institut Curie, CNRS-UMR144, Paris 75005, France.

Abstract

Directional transport of specific cargos is tuned to specific molecular motors and specific cytoskeletal tracks. Myosin V transports its cargo on actin cables, whereas kinesin or dynein transport their cargo on microtubules. A recent study shows that an engineered kinesin can substitute for myosin V and its cargo-specific transport and subsequent cellular functions.

Copyright © 2012 Elsevier Ltd. All rights reserved.

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PMID:
22280907
[PubMed - indexed for MEDLINE]
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