J Clin Microbiol. 2012 Apr;50(4):1458-60. Epub 2012 Jan 25.

Evaluation of a high-throughput diagnostic system for detection of HIV-1 in dried blood spot samples from infants in Mozambique.

Jani IV, Sabatier J, Vubil A, Subbarao S, Bila D, de Sousa A, Mabunda N, Garcia A, Skaggs B, Ellenberger D, Ramos A.

Source

Instituto Nacional de Saúde, Maputo, Mozambique.

Abstract

We performed a comparative analysis between Roche Amplicor HIV-1 DNA test and CAPTAQ assay for the detection of HIV in 830 dried blood spot (DBS) pediatric samples collected in Mozambique. Our results demonstrated no statistical difference between these assays. The CAPTAQ assay approached nearly 100% repeatability/accuracy. The increased throughput of testing with minimal operator interference in performing the CAPTAQ assay clearly demonstrated that this method is an improvement over the Roche Amplicor HIV-1 DNA test, version 1.5.

PMID:: 22278838; [PubMed - in process]
PMCID:: PMC3318546; [Available on 2012/10/1]

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Evaluation of a high-throughput diagnostic system for detection of HIV-1 in drie...
Evaluation of a high-throughput diagnostic system for detection of HIV-1 in dried blood spot samples from infants in Mozambique.
J Clin Microbiol. 2012 Apr ;50(4):1458-60. Epub 2012 Jan 25 .

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Evaluation of a high-throughput diagnostic system for detection of HIV-1 in dried blood spot samples from infants in Mozambique.

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