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    Results: 1 to 20 of 83

    1.

    New strategies in melanoma: molecular testing in advanced disease.

    Woodman SE, Lazar AJ, Aldape KD, Davies MA.

    Clin Cancer Res. 2012 Mar 1;18(5):1195-200. Epub 2012 Jan 24.

    PMID:
    22275506
    [PubMed - in process]
    2.

    CTLA-4 blockade with ipilimumab: long-term follow-up of 177 patients with metastatic melanoma.

    Prieto PA, Yang JC, Sherry RM, Hughes MS, Kammula US, White DE, Levy CL, Rosenberg SA, Phan GQ.

    Clin Cancer Res. 2012 Apr 1;18(7):2039-47. Epub 2012 Jan 23.

    PMID:
    22271879
    [PubMed - in process]
    3.

    Rehabilitation for oncogene addiction: role of immunity in cellular sobriety.

    Bajor DL, Vonderheide RH.

    Clin Cancer Res. 2012 Mar 1;18(5):1192-4. Epub 2012 Jan 20.

    PMID:
    22266272
    [PubMed - in process]
    4.

    Sunitinib therapy for melanoma patients with KIT mutations.

    Minor DR, Kashani-Sabet M, Garrido M, O'Day SJ, Hamid O, Bastian BC.

    Clin Cancer Res. 2012 Mar 1;18(5):1457-63. Epub 2012 Jan 18.

    PMID:
    22261812
    [PubMed - in process]
    5.

    Randomized phase II trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma (S0438).

    Margolin KA, Moon J, Flaherty LE, Lao CD, Akerley WL 3rd, Othus M, Sosman JA, Kirkwood JM, Sondak VK.

    Clin Cancer Res. 2012 Feb 15;18(4):1129-37. Epub 2012 Jan 6.

    PMID:
    22228638
    [PubMed - in process]
    6.

    Notch signaling promotes growth and invasion in uveal melanoma.

    Asnaghi L, Ebrahimi KB, Schreck KC, Bar EE, Coonfield ML, Bell WR, Handa J, Merbs SL, Harbour JW, Eberhart CG.

    Clin Cancer Res. 2012 Feb 1;18(3):654-65. Epub 2012 Jan 6.

    PMID:
    22228632
    [PubMed - indexed for MEDLINE]
    7.

    Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma.

    Davies MA, Fox PS, Papadopoulos NE, Bedikian AY, Hwu WJ, Lazar AJ, Prieto VG, Culotta KS, Madden TL, Xu Q, Huang S, Deng W, Ng CS, Gupta S, Liu W, Dancey JE, Wright JJ, Bassett RL, Hwu P, Kim KB.

    Clin Cancer Res. 2012 Feb 15;18(4):1120-8. Epub 2012 Jan 5.

    PMID:
    22223528
    [PubMed - in process]
    8.

    BRAF inhibitors for the treatment of metastatic melanoma: clinical trials and mechanisms of resistance.

    Alcalá AM, Flaherty KT.

    Clin Cancer Res. 2012 Jan 1;18(1):33-9.

    PMID:
    22215904
    [PubMed - indexed for MEDLINE]
    9.

    Modulation of NOXA and MCL-1 as a strategy for sensitizing melanoma cells to the BH3-mimetic ABT-737.

    Lucas KM, Mohana-Kumaran N, Lau D, Zhang XD, Hersey P, Huang DC, Weninger W, Haass NK, Allen JD.

    Clin Cancer Res. 2012 Feb 1;18(3):783-95. Epub 2011 Dec 15.

    PMID:
    22173547
    [PubMed - indexed for MEDLINE]
    10.

    Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma.

    Wilmott JS, Long GV, Howle JR, Haydu LE, Sharma RN, Thompson JF, Kefford RF, Hersey P, Scolyer RA.

    Clin Cancer Res. 2012 Mar 1;18(5):1386-94. Epub 2011 Dec 12.

    PMID:
    22156613
    [PubMed - in process]
    11.

    New challenges in endpoints for drug development in advanced melanoma.

    Ribas A, Hersey P, Middleton MR, Gogas H, Flaherty KT, Sondak VK, Kirkwood JM.

    Clin Cancer Res. 2012 Jan 15;18(2):336-41. Epub 2011 Dec 5.

    PMID:
    22142824
    [PubMed - in process]
    12.

    Lymphatic invasion is independently prognostic of metastasis in primary cutaneous melanoma.

    Xu X, Chen L, Guerry D, Dawson PR, Hwang WT, VanBelle P, Elder DE, Zhang PJ, Ming ME, Schuchter L, Gimotty PA.

    Clin Cancer Res. 2012 Jan 1;18(1):229-37. Epub 2011 Nov 17.

    PMID:
    22096024
    [PubMed - indexed for MEDLINE]
    13.

    Vemurafenib and BRAF inhibition: a new class of treatment for metastatic melanoma.

    Luke JJ, Hodi FS.

    Clin Cancer Res. 2012 Jan 1;18(1):9-14. Epub 2011 Nov 14.

    PMID:
    22083257
    [PubMed - indexed for MEDLINE]
    14.

    Phase II, open-label, randomized trial of the MEK1/2 inhibitor selumetinib as monotherapy versus temozolomide in patients with advanced melanoma.

    Kirkwood JM, Bastholt L, Robert C, Sosman J, Larkin J, Hersey P, Middleton M, Cantarini M, Zazulina V, Kemsley K, Dummer R.

    Clin Cancer Res. 2012 Jan 15;18(2):555-67. Epub 2011 Nov 2.

    PMID:
    22048237
    [PubMed - in process]
    15.

    Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma.

    Landreville S, Agapova OA, Matatall KA, Kneass ZT, Onken MD, Lee RS, Bowcock AM, Harbour JW.

    Clin Cancer Res. 2012 Jan 15;18(2):408-16. Epub 2011 Oct 28.

    PMID:
    22038994
    [PubMed - in process]
    16.

    A dose-escalation and signal-generating study of the immunocytokine L19-IL2 in combination with dacarbazine for the therapy of patients with metastatic melanoma.

    Eigentler TK, Weide B, de Braud F, Spitaleri G, Romanini A, Pflugfelder A, González-Iglesias R, Tasciotti A, Giovannoni L, Schwager K, Lovato V, Kaspar M, Trachsel E, Menssen HD, Neri D, Garbe C.

    Clin Cancer Res. 2011 Dec 15;17(24):7732-42. Epub 2011 Oct 25.

    PMID:
    22028492
    [PubMed - in process]
    17.

    Tumor-associated macrophages promote angiogenesis and melanoma growth via adrenomedullin in a paracrine and autocrine manner.

    Chen P, Huang Y, Bong R, Ding Y, Song N, Wang X, Song X, Luo Y.

    Clin Cancer Res. 2011 Dec 1;17(23):7230-9. Epub 2011 Oct 12.

    PMID:
    21994414
    [PubMed - indexed for MEDLINE]
    18.

    Multicenter, phase II study of axitinib, a selective second-generation inhibitor of vascular endothelial growth factor receptors 1, 2, and 3, in patients with metastatic melanoma.

    Fruehauf J, Lutzky J, McDermott D, Brown CK, Meric JB, Rosbrook B, Shalinsky DR, Liau KF, Niethammer AG, Kim S, Rixe O.

    Clin Cancer Res. 2011 Dec 1;17(23):7462-9. Epub 2011 Oct 5.

    PMID:
    21976544
    [PubMed - indexed for MEDLINE]
    19.

    Phase I/II and pharmacodynamic study of dovitinib (TKI258), an inhibitor of fibroblast growth factor receptors and VEGF receptors, in patients with advanced melanoma.

    Kim KB, Chesney J, Robinson D, Gardner H, Shi MM, Kirkwood JM.

    Clin Cancer Res. 2011 Dec 1;17(23):7451-61. Epub 2011 Oct 5.

    PMID:
    21976540
    [PubMed - indexed for MEDLINE]
    20.

    Molecular insights on the peripheral and intratumoral effects of systemic high-dose rIL-2 (aldesleukin) administration for the treatment of metastatic melanoma.

    Weiss GR, Grosh WW, Chianese-Bullock KA, Zhao Y, Liu H, Slingluff CL Jr, Marincola FM, Wang E.

    Clin Cancer Res. 2011 Dec 1;17(23):7440-50. Epub 2011 Oct 5.

    PMID:
    21976537
    [PubMed - indexed for MEDLINE]

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