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FASEB J. 1990 Nov;4(14):3256-60.

Whole-body imaging of the distribution of mercury released from dental fillings into monkey tissues.

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  • 1Department of Radiology, University of Calgary, Faculty of Medicine, Alberta, Canada.

Abstract

The fate of mercury (Hg) released from dental "silver" amalgam tooth fillings into human mouth air is uncertain. A previous report about sheep revealed uptake routes and distribution of amalgam Hg among body tissues. The present investigation demonstrates the bodily distribution of amalgam Hg in a monkey whose dentition, diet, feeding regimen, and chewing pattern closely resemble those of humans. When amalgam fillings, which normally contain 50% Hg, are made with a tracer of radioactive 203Hg and then placed into monkey teeth, the isotope appears in high concentration in various organs and tissues within 4 wk. Whole-body images of the monkey revealed that the highest levels of Hg were located in the kidney, gastrointestinal tract, and jaw. The dental profession's advocacy of silver amalgam as a stable tooth restorative material is not supported by these findings.

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PMID:
2227216
[PubMed - indexed for MEDLINE]
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