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Obstet Gynecol. 2012 Feb;119(2 Pt 2):423-6. doi: 10.1097/AOG.0b013e318234d97c.

Progestin intrauterine device in an adolescent with grade 2 endometrial cancer.

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  • 1Department of Gynecology and Obstetrics, the Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.

Abstract

BACKGROUND:

The treatment of endometrial cancer in young women who desire future fertility poses several challenges. Oral progestin and progestin-releasing intrauterine devices (IUDs) have been shown to result in regression of endometrial hyperplasia and grade 1 endometrioid endometrial carcinoma. However, limited data are available on the use of these methods in women with grade 2 disease.

CASE:

An 18-year-old nulliparous woman was diagnosed with a grade 2 endometrial adenocarcinoma. She desired future fertility and therefore underwent placement of a levonorgestrel-releasing IUD. The patient subsequently underwent endometrial sampling every 3 months and remained disease-free 13 months after initial IUD placement.

CONCLUSION:

A progestin-releasing IUD may be a valid treatment option for grade 2 endometrial cancer in young women who desire to retain fertility.

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PMID:
22270425
[PubMed - indexed for MEDLINE]
PMCID:
PMC3266511
Free PMC Article
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