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Genome Biol. 2012 Jan 23;13(1):237. doi: 10.1186/gb-2012-13-1-237.

What is complex about complex disorders?

Author information

  • Smurfit Institute of Genetics and Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland. Kevin.Mitchell@tcd.ie

Abstract

Rather than being polygenic, complex disorders probably represent umbrella terms for collections of conditions caused by rare, recent mutations in any of a large number of different genes.

PMID:
22269335
[PubMed - indexed for MEDLINE]
PMCID:
PMC3334577
Free PMC Article

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