Source
The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA. laurie@ccivf.com
Abstract
PURPOSE:
To determine if a successful pregnancy is possible following in vitro fertilization embryo transfer (IVF-ET) in a woman of advanced reproductive age with diminished egg reserve.
METHODS:
In vitro fertilization-embryo transfer with intracytoplasmic sperm injection (ICSI) was performed for a 45-year-old woman with a peak serum follicle stimulating hormone (FSH) level of 29 mIU/ml and a history of failing to conceive in five previous IVF-ET cycles at a younger age. A minimal FSH stimulation protocol was used.
RESULTS:
A fresh transfer of a 7-cell embryo was performed on day 3. A successful pregnancy and delivery ensued.
CONCLUSION:
This case report establishes a precedent that a successful pregnancy following IVF-ET is possible in a woman whose serum FSH is > 15 mIU/ml, and is age 45. Of course, there is no implication that accomplishing this again in another woman with similar circumstances would be likely.