Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Semin Neurol. 2011 Nov;31(5):553-61. doi: 10.1055/s-0031-1299793. Epub 2012 Jan 21.

Genetics meets environment: evaluating gene-environment interactions in neurologic diseases.

Author information

  • 1Toronto Western Hospital, University of Toronto, Ontario, Canada. cmarras@uhnresearch.ca

Abstract

The vast majority of disease is due to complex relationships between genetic and environmental factors. Single genetic or environmental causes are rare. Unfortunately, this presents major challenges for assessing disease risk in individuals. Further complicating the situation is the fact that there are many ways in which genetic and environmental determinants can combine to cause disease. This review explores the concepts of gene-environment interaction to provide a basic understanding of the principles of interactions and approaches to studying them. Collaborations between genetics and environmental experts will be crucial to understand the complex relationships.

© Thieme Medical Publishers.

PMID:
22266892
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Georg Thieme Verlag Stuttgart, New York
    Loading ...
    Write to the Help Desk