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Pulm Med. 2012;2012:249082. doi: 10.1155/2012/249082. Epub 2012 Jan 4.

Ancillary testing in lung cancer diagnosis.

Author information

  • 1Department of Pathology, Toronto General Hospital, University Health Network, 200 Elizabeth Street, Toronto, ON, Canada M5G 2C4.

Abstract

The pathologic diagnosis of lung cancer historically has relied primarily on morphologic features of tumors in histologic sections. With the emergence of new targeted therapies, the pathologist is called upon increasingly to provide not only accurate typing of lung cancers, but also to provide prognostic and predictive information, based on a growing number of ancillary tests, that may have significant impact on patient management. This review provides an overview of ancillary tests currently used in the pathologic diagnosis of lung cancer, with a focus on immunohistochemistry and molecular diagnostics.

PMID:
22263108
[PubMed]
PMCID:
PMC3259481
Free PMC Article

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