Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Virol. 2012 Mar;86(6):2900-10. doi: 10.1128/JVI.05738-11. Epub 2012 Jan 18.

Sensing of RNA viruses: a review of innate immune receptors involved in recognizing RNA virus invasion.

Author information

  • 1Institute of International Health, Immunology, and Microbiology, University of Copenhagen, Copenhagen, Denmark.

Abstract

Our knowledge regarding the contribution of the innate immune system in recognizing and subsequently initiating a host response to an invasion of RNA virus has been rapidly growing over the last decade. Descriptions of the receptors involved and the molecular mechanisms they employ to sense viral pathogen-associated molecular patterns have emerged in great detail. This review presents an overview of our current knowledge regarding the receptors used to detect RNA virus invasion, the molecular structures these receptors sense, and the involved downstream signaling pathways.

PMID:
22258243
[PubMed - indexed for MEDLINE]
PMCID:
PMC3302314
Free PMC Article

Images from this publication.See all images (2)Free text

Fig 1
Fig 2
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk