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    Eur J Cancer. 2012 Mar;48(4):482-91. Epub 2012 Jan 16.

    Combining capecitabine and bevacizumab in metastatic breast cancer: a comprehensive review.

    Miles D, Zielinski C, Martin M, Vrdoljak E, Robert N.

    Source

    Mount Vernon Cancer Centre, Northwood, UK.

    Abstract

    Both capecitabine and bevacizumab are established agents in the treatment of metastatic breast cancer, but until recently clinical data supporting their use in combination were limited. We review available data on the capecitabine-bevacizumab combination in breast cancer, particularly results from the RIBBON-1 trial in the first-line setting, and we discuss these findings in light of previous studies. We also examine ongoing trials investigating capecitabine-bevacizumab combination therapy.

    Copyright © 2012. Published by Elsevier Ltd.

    PMID:
    22257791
    [PubMed - indexed for MEDLINE]

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