Clinical trials for glaucoma neuroprotection are not impossible

Curr Opin Ophthalmol. 2012 Mar;23(2):144-54. doi: 10.1097/ICU.0b013e32834ff490.

Abstract

Purpose of review: To discuss issues that affect development of new glaucoma treatments known as neuroprotection.

Recent findings: There are barriers to neuroprotection trials for glaucoma.

Summary: With design features discussed in the review, neuroprotection trials can be effectively carried out.

Publication types

  • Review

MeSH terms

  • Animals
  • Clinical Trials as Topic
  • Disease Models, Animal
  • Glaucoma / prevention & control*
  • Humans
  • Nerve Fibers / drug effects*
  • Neuroprotective Agents / therapeutic use*
  • Optic Nerve Diseases / prevention & control*
  • Retinal Ganglion Cells / drug effects*

Substances

  • Neuroprotective Agents