Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Neurogastroenterol Motil. 2012 Mar;24 Suppl 1:32-9. doi: 10.1111/j.1365-2982.2011.01837.x.

Esophageal hypertensive peristaltic disorders.

Author information

  • 1Digestive Physiology, Hopsices Civils de Lyon, Hospital E Herriot, and Lyon I University, Lyon, France. roman.sabine@gmail.com

Abstract

BACKGROUND:

Esophageal motility abnormalities include a series of manometric findings that differ to a significant degree from findings in normal, asymptomatic volunteers.

METHODS:

Current review summarizes conventional and high-resolution esophageal manometry criteria used to define and characterize esophageal hypertensive motility abnormalities.

KEY RESULTS:

In the conventional esophageal manometry classification scheme hypertensive esophageal motility abnormalities include nutcracker esophagus (average distal contraction amplitude >180 mmHg), hypertensive lower esophageal sphincter (average resting LES pressure >45 mmHg) and poorly relaxing lower esophageal sphincter (average LES residual pressure >8 mmHg). The new, high resolution esophageal manometry scheme includes in the group of hypertensive peristaltic disorders hypertensive peristalsis ("nutcracker esophagus": mean DCI >5000 mmHg*sec*cm) and hypercontractile esophagus ("jackhammer esophagus": at least one contraction with DCI > 8,000 mmHg*sec*cm) and defines a separate group for disorders with impaired esophageal-gastric junction relaxation (mean integrated residual (LES) pressure >15 mmHg).

CONCLUSIONS & INFERENCES:

Hypertensive motility disorders represent a heterogeneous condition subdivided into hypercontractile esophagus and hypertensive peristalsis. Further studies are required to determine the clinical relevance of this new classification.

© 2012 Blackwell Publishing Ltd.

PMID:
22248106
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Blackwell Publishing
    Loading ...
    Write to the Help Desk