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Trends Ecol Evol. 2012 Apr;27(4):233-43. doi: 10.1016/j.tree.2011.11.010. Epub 2012 Jan 11.

Sequencing our way towards understanding global eukaryotic biodiversity.

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  • 1Hubbard Center for Genome Studies, University of New Hampshire, 35 Colovos Rd, Durham, NH 03824, USA.


Microscopic eukaryotes are abundant, diverse and fill critical ecological roles across every ecosystem on Earth, yet there is a well-recognized gap in understanding of their global biodiversity. Fundamental advances in DNA sequencing and bioinformatics now allow accurate en masse biodiversity assessments of microscopic eukaryotes from environmental samples. Despite a promising outlook, the field of eukaryotic marker gene surveys faces significant challenges: how to generate data that are most useful to the community, especially in the face of evolving sequencing technologies and bioinformatics pipelines, and how to incorporate an expanding number of target genes.

Copyright © 2011 Elsevier Ltd. All rights reserved.

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