J Pediatr. 2012 Mar;160(3):520-2. Epub 2012 Jan 13.

Abatacept and sodium thiosulfate for treatment of recalcitrant juvenile dermatomyositis complicated by ulceration and calcinosis.

Arabshahi B, Silverman RA, Jones OY, Rider LG.

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Division of Pediatric Rheumatology, Department of Pediatrics, Inova Fairfax Hospital for Children, Fairfax, VA 22031, USA. bita.arabshahi@inova.org

Abstract

We report the successful use of abatacept and sodium thiosulfate in a patient with severe recalcitrant juvenile dermatomyositis complicated by ulcerative skin disease and progressive calcinosis. This combination therapy resulted in significant reductions in muscle and skin inflammation, decreased corticosteroid dependence, and halted the progression of calcinosis.

PMID:: 22244459; [PubMed - indexed for MEDLINE]
PMCID:: PMC3306811; [Available on 2013/3/1]

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