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    Results: 1 to 20 of 23

    1.

    Probing structural features of Alzheimer's amyloid-β pores in bilayers using site-specific amino acid substitutions.

    Capone R, Jang H, Kotler SA, Kagan BL, Nussinov R, Lal R.

    Biochemistry. 2012 Jan 24;51(3):776-85. Epub 2012 Jan 12.

    PMID:
    22242635
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Induction of methionine-sulfoxide reductases protects neurons from amyloid β-protein insults in vitro and in vivo.

    Moskovitz J, Maiti P, Lopes DH, Oien DB, Attar A, Liu T, Mittal S, Hayes J, Bitan G.

    Biochemistry. 2011 Dec 13;50(49):10687-97. Epub 2011 Nov 14.

    PMID:
    22059533
    [PubMed - indexed for MEDLINE]
    3.

    Dynamics in the active site of β-secretase: a network analysis of atomistic simulations.

    Mishra S, Caflisch A.

    Biochemistry. 2011 Nov 1;50(43):9328-39. Epub 2011 Oct 5.

    PMID:
    21942621
    [PubMed - indexed for MEDLINE]
    4.

    Hydrogen/deuterium exchange and electron-transfer dissociation mass spectrometry determine the interface and dynamics of apolipoprotein E oligomerization.

    Huang RY, Garai K, Frieden C, Gross ML.

    Biochemistry. 2011 Nov 1;50(43):9273-82. Epub 2011 Oct 5.

    PMID:
    21899263
    [PubMed - indexed for MEDLINE]
    5.

    Distinguishing amyloid fibril structures in Alzheimer's disease (AD) by two-dimensional ultraviolet (2DUV) spectroscopy.

    Lam AR, Jiang J, Mukamel S.

    Biochemistry. 2011 Nov 15;50(45):9809-16. Epub 2011 Oct 20.

    PMID:
    21961527
    [PubMed - indexed for MEDLINE]
    6.

    Dissociation between the processivity and total activity of γ-secretase: implications for the mechanism of Alzheimer's disease-causing presenilin mutations.

    Quintero-Monzon O, Martin MM, Fernandez MA, Cappello CA, Krzysiak AJ, Osenkowski P, Wolfe MS.

    Biochemistry. 2011 Oct 25;50(42):9023-35. Epub 2011 Sep 30.

    PMID:
    21919498
    [PubMed - indexed for MEDLINE]
    7.

    The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

    Dinamarca MC, Weinstein D, Monasterio O, Inestrosa NC.

    Biochemistry. 2011 Sep 27;50(38):8127-37. Epub 2011 Sep 1.

    PMID:
    21838267
    [PubMed - indexed for MEDLINE]
    8.

    Single-molecule atomic force microscopy force spectroscopy study of Aβ-40 interactions.

    Kim BH, Palermo NY, Lovas S, Zaikova T, Keana JF, Lyubchenko YL.

    Biochemistry. 2011 Jun 14;50(23):5154-62. Epub 2011 May 17.

    PMID:
    21553928
    [PubMed - indexed for MEDLINE]
    9.

    Mutations that replace aromatic side chains promote aggregation of the Alzheimer's Aβ peptide.

    Armstrong AH, Chen J, McKoy AF, Hecht MH.

    Biochemistry. 2011 May 17;50(19):4058-67. Epub 2011 Apr 22.

    PMID:
    21513285
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    10.

    Regulation of insulin-regulated membrane aminopeptidase activity by its C-terminal domain.

    Ascher DB, Cromer BA, Morton CJ, Volitakis I, Cherny RA, Albiston AL, Chai SY, Parker MW.

    Biochemistry. 2011 Apr 5;50(13):2611-22. Epub 2011 Mar 9.

    PMID:
    21348480
    [PubMed - indexed for MEDLINE]
    11.

    S-nitrosylation of ApoE in Alzheimer's disease.

    Abrams AJ, Farooq A, Wang G.

    Biochemistry. 2011 May 3;50(17):3405-7. Epub 2011 Apr 6.

    PMID:
    21443265
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    12.

    The amyloid precursor protein C-terminal fragment C100 occurs in monomeric and dimeric stable conformations and binds γ-secretase modulators.

    Botev A, Munter LM, Wenzel R, Richter L, Althoff V, Ismer J, Gerling U, Weise C, Koksch B, Hildebrand PW, Bittl R, Multhaup G.

    Biochemistry. 2011 Feb 8;50(5):828-35. Epub 2011 Jan 11.

    PMID:
    21186781
    [PubMed - indexed for MEDLINE]
    13.

    Inhibition mechanism of rat α₃β₄ nicotinic acetylcholine receptor by the Alzheimer therapeutic tacrine.

    Cheffer A, Ulrich H.

    Biochemistry. 2011 Mar 22;50(11):1763-70. Epub 2011 Feb 28.

    PMID:
    21247200
    [PubMed - indexed for MEDLINE]
    14.

    Polyhistidine peptide inhibitor of the Abeta calcium channel potently blocks the Abeta-induced calcium response in cells. Theoretical modeling suggests a cooperative binding process.

    Arispe N, Diaz J, Durell SR, Shafrir Y, Guy HR.

    Biochemistry. 2010 Sep 14;49(36):7847-53.

    PMID:
    20690616
    [PubMed - indexed for MEDLINE]
    15.

    A disulfide-linked amyloid-beta peptide dimer forms a protofibril-like oligomer through a distinct pathway from amyloid fibril formation.

    Yamaguchi T, Yagi H, Goto Y, Matsuzaki K, Hoshino M.

    Biochemistry. 2010 Aug 24;49(33):7100-7.

    PMID:
    20666485
    [PubMed - indexed for MEDLINE]
    16.

    Mutations alter the geometry and mechanical properties of Alzheimer's Aβ(1-40) amyloid fibrils.

    Paparcone R, Pires MA, Buehler MJ.

    Biochemistry. 2010 Oct 19;49(41):8967-77.

    PMID:
    20731379
    [PubMed - indexed for MEDLINE]
    17.

    Engineered proteolytic nanobodies reduce Abeta burden and ameliorate Abeta-induced cytotoxicity.

    Kasturirangan S, Boddapati S, Sierks MR.

    Biochemistry. 2010 Jun 1;49(21):4501-8.

    PMID:
    20429609
    [PubMed - indexed for MEDLINE]
    18.
    19.

    Elucidation of interactions of Alzheimer amyloid beta peptides (Abeta40 and Abeta42) with insulin degrading enzyme: a molecular dynamics study.

    Bora RP, Prabhakar R.

    Biochemistry. 2010 May 11;49(18):3947-56.

    PMID:
    20380468
    [PubMed - indexed for MEDLINE]
    20.

    Destabilizing Alzheimer's Abeta(42) protofibrils with morin: mechanistic insights from molecular dynamics simulations.

    Lemkul JA, Bevan DR.

    Biochemistry. 2010 May 11;49(18):3935-46.

    PMID:
    20369844
    [PubMed - indexed for MEDLINE]

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