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    Chem Commun (Camb). 2012 Feb 18;48(15):2131-3. Epub 2012 Jan 13.

    Ternary resin-bound dynamic combinatorial chemistry.

    Source

    Department of Dermatology, University of Rochester Medical Center, Rochester, New York, USA. Benjamin_Miller@urmc.rochester.edu.

    Abstract

    The ability to carry out simultaneous orthogonal exchange chemistries has opened new opportunities for increasing the numerical and structural diversity accessible to Dynamic Combinatorial Chemistry. We present proof-of-concept experiments demonstrating this concept is transferrable to resin-bound DCC, facilitating the generation and analysis of libraries with greater structural diversity.

    PMID:
    22240966
    [PubMed - in process]

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