Wound healing: calcium flashes illuminate early events

Will Wood

doi:10.1016/j.cub.2011.11.019

Wound healing: calcium flashes illuminate early events

Curr Biol. 2012 Jan 10;22(1):R14-6. doi: 10.1016/j.cub.2011.11.019.

Author

Will Wood¹

Affiliation

¹ Centre for Regenerative Medicine, Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK. w.wood@bath.ac.uk

PMID: 22240471
DOI: 10.1016/j.cub.2011.11.019

Abstract

What are the earliest signals produced at a wound edge that mobilise epithelial cells to heal the wound? Live analysis of wound healing in the worm Caenorhabditis elegans shows that calcium may be the key early trigger.

Publication types

Comment

MeSH terms

Animals
Caenorhabditis elegans / immunology*
Calcium / metabolism*
Epidermis / immunology*
GTP-Binding Protein alpha Subunits, Gq-G11 / metabolism*
Signal Transduction / immunology*
Wound Healing / immunology*

Substances

GTP-Binding Protein alpha Subunits, Gq-G11
Calcium

Grants and funding

090899/WT_/Wellcome Trust/United Kingdom