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J Infect Dis. 2012 Mar 1;205(5):789-93. doi: 10.1093/infdis/jir851. Epub 2012 Jan 11.

Risk factors for incident condyloma in a multinational cohort of men: the HIM study.

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  • 1Department of Cancer Epidemiology, Moffitt Cancer Center and Research Institute, Tampa, FL, USA. anna.giuliano@moffitt.org


Identifying factors associated with condyloma are necessary for prevention efforts. Risk factors for incident condyloma were examined in a cohort of 2487 men from the United States, Brazil, and Mexico and were followed up every 6 months (median, 17.9 months). Factors strongly associated with condyloma were incident infection with human papillomavirus (HPV) types 6 and 11 (hazard ratio [HR], 12.42 [95% confidence interval {CI}, 3.78-40.77]), age (HR, 0.43 [95% CI, .26-.77]; 45-70 vs 18-30 years), high lifetime number of female partners (HR, 5.69 [95% CI, 1.80-17.97]; ≥21 vs 0 partners), and number of male partners (HR, 4.53 [95% CI, 1.68-12.20]; ≥3 vs 0 partners). The results suggest that HPV types 6 and 11 and recent sexual behavior are strongly associated with incident condyloma.

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