Format

Send to:

Choose Destination
See comment in PubMed Commons below
Orthopedics. 2012 Jan;35(1):52-60. doi: 10.3928/01477447-20111122-23.

Dupuytren's disease.

Author information

  • 1Department of Orthopedic Surgery, Mercy St Vincent Medical Center, Toledo, Ohio, USA.

Abstract

Dupuytren's disease is a benign contractile disorder of the hand. The condition commonly affects older men of Celtic descent. Although fibroproliferation and collagen alteration play a role in its etiology, defining a cause remains elusive. Nonoperative intervention for advanced disease has shown only short-term benefit. Therefore, open fasciectomy has become the mainstay of treatment. Associated morbidity and recurrence have prompted investigation into less invasive techniques, including needle aponeurotomy and enzymatic fasciotomy. Data from phase III studies using injectable collagenase are changing treatment algorithms. Postoperative rehabilitation includes nighttime splinting and immediate active range of motion exercises to facilitate return to function.

Copyright 2012, SLACK Incorporated.

PMID:
22229922
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for SLACK Incorporated.
    Loading ...
    Write to the Help Desk